Travelers seeking memorable experiences often turn to unique hotels that offer more than just a place to sleep.

Check out our picks below!

Outside, the inn’s sprawling grounds offer a wealth of amenities and activities for guests to enjoy.

Most Unique Hotels in the U.S.

Fun fact: The name of the inn has nothing to do with Madonna the performer.

Guests can learn all about the alleged apparitions during a guided, one-hour haunted history tour.

What do you see?

Most Unique Hotels in the U.S.

Booking.com| From $498/night

An ode to Willy Wonka?

Piped frosting from a wedding cake on a hot day?

How about a giant seashell unicorn?

Landoll’s Mohican Castle

Kayak| From $157/night

The award-winning structure started with a hippie dream that took 11 years to build.

It has been heralded as a masterpiece where architecture and nature come together in perfect harmony.

This one-of-a-kind destination boasts a whopping 62 eco-friendly geodesic domes with floor-to-ceiling windows and panoramic views.

The Villa Casa Casuarina

Booking.com| From $1,348/night

More than just a feast for the eyes, The Roxbury is also a haven of comfort.

It was repurposed in 2017 and redesigned into the luxurious hotel it is today.

Its storied past only adds to its intrigue and allure.

Bloomhouse by Lodgewell

VRBO| Pricing varies based on availability

Despite its checkered past, it still manages to provide a serene and sophisticated stay.

Each trailer has unique decor and charm thats perfect for a glamping getaway in Wine Country.

If you gotta stock up on drinks or snacks, the on-site general store has you covered.

Most Unique Hotels in the U.S.

Booking.com| From $909/night

The interiors seamlessly blend historical charm with all the contemporary amenities you need for a comfortable stay.

One of the best things about this hotel is its proximity to Wine Country.

The inn provides easy access to some of the regions finest wineries and tasting rooms.

Most Unique Hotels in the U.S.

Booking.com| From $297/night

In 1973, the prisoners revolted because of poor living conditions and the jail was declared unfit.

Guests can dine at the aptly named CLINK restaurant, where bars still adorn the original windows.

And the jails former exercise yard is now a private, beautifully landscaped courtyard.

Aurora Villa

Booking.com| From $1,000/night

Like-minded travelers come together to share stories, swap tips, and embrace the spirit of adventure.

Bikes are even available to rent, as are wood-fired Dutch hot tubs (with 24-hour advance notice).

The Queen Mary

Booking.com| From $328/night

The Richardson

Booking.com| From $448/night

The Vintages Trailer Resort

Booking.com| From $328/night

Napa Valley Railway Inn

Expedia| From $316/night

Most Unique Hotels in the U.S.

Booking.com| From $661/night

Liberty Hotel

Booking.com| From $1,594/night

El Cosmico

Booking.com| From $198/night